Sclerostin antibody (N-Term)

Catalog No. ABIN1539331

This Rabbit Polyclonal antibody specifically detects Sclerostin in WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for Sclerostin antibody (N-Term) (ABIN1539331)

Target: Sclerostin (SOST)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Sclerostin antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB36187

Product Details anti-Sclerostin Antibody

Binding Specificity: AA 38-66, N-Term

Predicted Reactivity: B

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SOST antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-66 amino acids from the N-terminal region of human SOST.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: SOST Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for Sclerostin

Target: Sclerostin (SOST)

Alternative Name: SOST

Background: Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease. [provided by RefSeq].

Molecular Weight: 24031

Gene ID: 50964

NCBI Accession: NP_079513

UniProt: Q9BQB4